Upstream Industrial Biotechnology: Expression Systems and Process Development (1ST ed.)
|
Marc Notes: VOLUME I: EXPRESSION SYSTEMS & PROCESS DEVELOPMENT PREFACE xi CONTRIBUTORS xiii PART I INTRODUCTION 3 PART II INDUSTRIAL CELL GROWTH AND GENE EXPRESSION SYSTEMS 7 1 Animal Cells, Suspension Culture 9 2 Baculovirus Expression Systems 19 3 Baculovirus Kinetics, Insect Culture 33 4 Cell Culture, Aseptic Techniques 49 5 Cell Cycle in Bioprocesses 71 6 Cell Growth and Protein Expression Kinetics 85 7 Cell Viability Measurement 97 8 Contamination Detection in Animal Cell Culture 105 9 Culture Collections and Biological Resource Centers (BRCs) 131 10 Culture Preservation 153 11 Expression and Secretion of Heterologous Proteins, Bacillus and Other Gram-Positive Bacteria 163 12 Gene Expression in Human Cells 181 13 Gene expression in Pichia and other methylotroph yeast 195 14 Gene Expression in Recombinant Animal Cells and Transgenic Animals 213 15 Inoculum Expansion Methods, Animal Cell Lines 297 16 Insect Cell Culture 311 17 Kinetics of Microbial Growth 331 18 Microalgae, Mass Culture Methods 371 19 Microbial Growth Measurement 399 20 Microbial Media Composition 413 21 Microscopic Characterization of Cells 437 22 Mycoplasma Contamination of Cell Cultures 467 23 Protein Glycosylation: Analysis, Characterization, and Engineering 489 24 Secretion of Heterologous Proteins, Gram Positive Bacteria 543 25 Soluble Protein Expression in Bacteria 557 PART III MEDIA, CELL LINES AND PROCESS DEVELOPMENT 579 26 Animal Cell Culture Media 581 27 Animal Cell Culture, Effects of Osmolality and Temperature 599 28 Animal Cell Stability 617 29 Animal Cell Types, Hybridomas 635 30 Antibody Production, Human Recombinant 645 31 Antifoams and Pluronic Polyols, Cell Protection 663 32 Biominiaturization of Bioreactors 669 33 Inoculum Preparation 699 34 Microcarrier Culture 711 35 Monoclonal Antibody Production, Cell Lines 733 36 Plant Cell Culture, Laboratory Techniques 747 37 Scale-Up of Biotechnological Processes 759 VOLUME II: EQUIPMENT, PROCESS DESIGN, SENSING, CONTROL, AND cGMP OPERATIONS PREFACE ix CONTRIBUTORS xi PART IV BIOREACTOR DESIGN, ENGINEERING, PROCESS SENSING AND CONTROL 789 38 Aeration, Mixing, and Hydrodynamics in Animal Cell Bioreactors 791 39 Biocatalytic Membrane Reactors 821 40 Bioreactor Scale-Down 847 41 Bioreactor Scale-Up 863 42 Bioreactors: Airlift Reactors 887 43 Bioreactors, Continuous Culture of Plant Cells 955 44 Bioreactors, Fluidized-Bed 963 45 Bioreactors, Gas-Treatment 979 46 Bioreactors, Perfusion 995 47 Bioreactors: Rotating Biological Contactors 1013 48 Bioreactors, Stirred Tank for Culture of Plant Cells 1031 49 Cell Immobilization, Engineering Aspects 1069 50 Fermenter/Bioreactor Design 1101 51 Gas-Holdup in Bioreactors 1137 52 Immobilization of Proteins and Enzymes, Mesoporous Supports 1147 53 Immobilized Cells 1179 54 Immobilized Enzymes 1201 55 Impeller Selection, Animal Cell Culture 1219 56 Mammalian Cell Bioreactors 1233 57 Mammalian Cell Culture Reactors, Scale-Up 1245 58 Mass Transfer 1261 59 Oxygen Transfer Rate Determination Methods 1303 60 Photobioreactors 1327 61 Rheological Behavior of Fermentation Fluids 1347 62 Rheology of Filamentous Microorganisms, Submerged Culture 1359 63 Sampling and Sample Handling for Process Control 1377 64 Solid State Fermentation, Kinetics 1387 65 Solid Substrate Fermentation, Automation 1413 66 Stainless Steels 1427 67 Static Mixing, Fermentation Processes 1435 68 Transfer Phenomena in Multiphase Systems 1451 PART V PROCESS ANALYTICAL TECHNOLOGIES (PAT) 1469 69 Bioprocess and Fermentation Monitoring 1471 70 Flow Injection Analysis in Industrial Biotechnology 1493 71 Fluorescence Techniques for Bioprocess Monitoring 1511 72 Off-Line Analysis in Animal Cell Culture 1523 73 Process Analytical Technology: Strategies for Biopharmaceuticals 1543 74 Vent Gas Analysis 1567 PART VI UPSTREAM cGMP OPERATIONS 1585 75 Antibody Manufacture, Disposable Systems 1587 76 Bioreactor Operations 1595 77 Bioreactors, Cell Culture, Commercial Production 1635 78 Biotransformation, Process Optimization 1665 79 Foam Formation and Control in Bioreactors 1679 80 Pilot Plants, Design and Operation 1695 81 Shear Sensitivity 1719 82 Sterilization and Decontamination, Bioprocess Equipment 1763 INDEX 1781 Biographical Note: Editor-in-Chief, Dr. Michael C. Flickinger is the Associate Director for Academic Programs of the Golden LEAF Biomanufacturing Training and Education Center (BTEC) and a Professor of Microbiology and Chemical and Biomolecular Engineering at North Carolina State University, Raleigh. Publisher Marketing: Biotechnology represents a major area of research focus, and many universities are developing academic programs in the field. This guide to biomanufacturing contains carefully selected articles from Wiley's Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell Technology as well as new articles (80 in all, ) and features the same breadth and quality of coverage and clarity of presentation found in the original. For instructors, advanced students, and those involved in regulatory compliance, this two-volume desk reference offers an accessible and comprehensive resource. |
){kind=link}
Spiral Bound Books
(Over 50,000+ Books)
Adult Ccrn Exam Premium: Study Guide for the Latest Exam Blueprint, Includes 3 Practice Tests, Comprehensive Review, and Online Study Prep (Barron's Test Prep) (3RD ed.) (Spiral Bound)
100 of the Most Beautiful Piano Solos Ever - Piano Sheet Music Book (Created by) (Spiral Bound)
The Complete Mediterranean Cookbook: 500 Vibrant, Kitchen-Tested Recipes for Living and Eating Well Every Day (The Complete Atk Cookbook) (Spiral Bound)
The New York Times Mega Book of Sunday Crosswords: 500 Puzzles (Spiral Bound)
The Complete Guide to Pressure Canning: Everything You Need to Know to Can Meats, Vegetables, Meals in a Jar, and More (Spiral Bound)
The Bible Recap: A One-Year Guide to Reading and Understanding the Entire Bible (Spiral Bound)
Couple's Bible Study Activities: 70 Engaging Activities to Connect with Your Faith and Each Other (Spiral Bound)
